CACNA1C articles on Wikipedia
Cav1.2
subunit (also known as Cav1.2) is a protein that in humans is encoded by the CACNA1C gene. Cav1.2 is a subunit of L-type voltage-dependent calcium channel.
Apr 4th 2017



CACNA1H
Calcium channel, voltage-dependent, T type, alpha 1H subunit, also known as CACNA1H, is a protein which in humans is encoded by the CACNA1H gene. This
Feb 6th 2017



CACNA2D1
Voltage-dependent calcium channel subunit alpha-2/delta-1 is a protein that in humans is encoded by the CACNA2D1 gene. This gene encodes a member of the
Feb 6th 2017



Cav1.4
Cav1.4 also known as the calcium channel, voltage-dependent, L type, alpha 1F subunit (CACNA1F), is a human gene. This gene encodes a member of the alpha-1
May 22nd 2016



CACNA2D2
Voltage-dependent calcium channel subunit alpha2delta-2 is a protein that in humans is encoded by the CACNA2D2 gene. This gene encodes a member of the
Feb 6th 2017



Cav1.1
Cav1.1 also known as the calcium channel, voltage-dependent, L type, alpha 1S subunit, (CACNA1S), is a protein which in humans is encoded by the CACNA1S
May 19th 2016



CACNA2D3
Calcium channel, voltage-dependent, alpha 2/delta subunit 3 is a protein that in humans is encoded by the CACNA2D3 gene on chromosome 3 (locus 3p21.1)
Feb 6th 2017



Cav2.1
The Cav2.1 P/Q voltage-dependent calcium channel is encoded by the CACNA1A gene. Voltage-dependent calcium channels mediate the entry of calcium ions
Jun 8th 2016



Cav1.3
Calcium channel, voltage-dependent, L type, alpha 1D subunit (also known as Cav1.3) is a protein that in humans is encoded by the CACNA1D gene. Cav1.3
Nov 30th 2016



L-type calcium channel
S5-S6 subunits make up the selectivity filter. CACNA1C, CACNA1D, CACNA1S, CACNA1F CACNA1C CACNA1D CACNA1S CACNA1F Felizola SJ, Maekawa T, Nakamura
Apr 24th 2017



R-type calcium channel
The R-type calcium channel is a type of voltage-dependent calcium channel. Like the others of this class, the α1 subunit forms the pore through which calcium
Apr 24th 2017



CACNA2D4
Calcium channel, voltage-dependent, alpha 2/delta subunit 4 is a protein that in humans is encoded by the CACNA2D4 gene. This gene encodes a member
Feb 6th 2017



Episodic ataxia
Episodic ataxia (EA) is an autosomal dominant disorder characterized by sporadic bouts of ataxia (severe discoordination) with or without myokymia (continuous
Mar 4th 2017



Timothy syndrome
caused by mutations in CACNA1C, the gene encoding the calcium channel Cav1.2 α subunit. Timothy syndrome mutations in CACNA1C cause delayed channel closing
Mar 28th 2017



X-linked congenital stationary night blindness
X-linked congenital stationary night blindness (CSNB) is a rare X-linked non-progressive retinal disorder. It has two forms, complete, also known as type-1
Jun 21st 2016



Childhood absence epilepsy
Childhood absence epilepsy (CAE), also known as pyknolepsy, is an idiopathic generalized epilepsy which occurs in otherwise normal children. The age of
Mar 4th 2017



CACNA1B
The voltage-dependent N-type calcium channel subunit alpha-1B is a protein that in humans is encoded by the CACNA1B gene. "Drugs that physically interact
Apr 6th 2017



N-type calcium channel
N-type calcium channels are voltage gated calcium channels that are distributed throughout the entire body. These channels are high voltage activated channels
Apr 26th 2017



Familial hemiplegic migraine
Familial hemiplegic migraine (FHM) is an autosomal dominant classical migraine subtype that typically includes weakness of half the body which can last
Mar 16th 2017



Calcium-binding protein 1
membranes via C-terminal calcium binding motif. It also interacts with CACNA1C via C-terminal C and IQ motifs. It interacts with TRPC5 and also interacts
Nov 24th 2016



Ion channel family
TRPV5; TRPV6 MCOLN1; MCOLN2; MCOLN3; TRPA1 PKD1L3; CACNA1A; CACNA1B; CACNA1C; CACNA1D; CACNA1E; CACNA1F; CACNA1G; CACNA1H; CACNA1I; CACNA1S CATSPER1;
Aug 13th 2016



Voltage-dependent calcium channel
"DHP Receptor") HVA (high voltage activated) Cav1.1 (CACNA1S) Cav1.2 (CACNA1C) Cav1.3 (CACNA1D) Cav1.4 (CACNA1F) α2δ, β, γ Skeletal muscle, smooth muscle
Mar 10th 2017



Spinocerebellar ataxia type 6
Spinocerebellar ataxia type 6 (SCA6SCA6) is a rare, late-onset, autosomal dominant disorder, which, like other types of SCA, is characterized by dysarthria
Jun 21st 2016



Sophia Frangou
R.; Girardi, P.; Collier, D.; Frangou, S. (2011). "The impact of the CACNA1C gene polymorphism on frontolimbic function in bipolar disorder". Mol Psychiatry
Nov 2nd 2016



Von Willebrand factor type A domain
The von Willebrand factor is a large multimeric glycoprotein found in blood plasma. Mutant forms are involved in the aetiology of bleeding disorders. In
Jun 6th 2016



Pamela Sklar
and the alpha-1C subunit of the L-type voltage-gated calcium channel (CACNA1C) in bipolar disorder. Nat Genet 40:1056-8. International Schizophrenia
Feb 22nd 2017



Endophenotype
anterior cingulate cortex, striatum, and amygdala. A polymorphism in the CACNA1C gene coding for the voltage-dependent calcium channel Cav1.2 has been found
Mar 19th 2017



Ankyrin
"Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder". Nat. Genet. 40 (9): 1056–8. doi:10.1038/ng.209. PMC 2703780
Dec 6th 2016



P-type calcium channel
The P-type calcium channel is a type of voltage-dependent calcium channel. Similar to many other high-voltage-gated calcium channels, the α1 subunit determines
Apr 24th 2017



Index of biophysics articles
This is a list of articles on biophysics. Contents : Top 0–9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 5-HT3 receptor ACCN1 ANO1 AP2 adaptor
Aug 14th 2014



Chromosome 3 (human)
Chromosome 3 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 3 spans almost 200 million
Apr 26th 2017



Nyctalopin
Nyctalopin is a protein that in humans is encoded by the NYX gene. It is a leucine-rich proteoglycan which is expressed in the eye, spleen and brain in
Jul 30th 2016



Brugada syndrome
Antzelevitch has identified mutations in the L-type calcium channel subunits (CACNA1C (A39V and G490R) and CACNB2 (S481L)) leading to ST elevation and a relatively
Apr 18th 2017



Li Tao (psychologist)
Zhiqiang; Chen, JianhuaJianhua; Li, Wenjin; Wang, Ti; Ji, Jue (2014-01-01). "CACNA1C, schizophrenia and major depressive disorder in the Han Chinese population"
Apr 4th 2017



ANK3
"Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder". Nat. Genet. 40 (9): 1056–8. doi:10.1038/ng.209. PMC 2703780
Mar 28th 2017



Ribbon synapse
The ribbon synapse is a type of neuronal synapse characterized by the presence of an electron-dense structure, the synaptic ribbon, that holds vesicles
Apr 25th 2017



CACNB4
Voltage-dependent L-type calcium channel subunit beta-4 is a protein that in humans is encoded by the CACNB4 gene. This gene encodes a member of the
Feb 6th 2017



Chromosome 19 (human)
Chromosome 19 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 19 spans more than 58.6 million
Mar 26th 2017



Nystagmus
Nystagmus is a condition of involuntary (or voluntary, in rare cases) eye movement, acquired in infancy or later in life, that may result in reduced or
Apr 24th 2017



Long QT syndrome
is due to mutations in the calcium channel Cav1.2 encoded by the gene CACNA1c. Since the calcium channel Cav1.2 is abundant in many tissues, patients
Apr 24th 2017



Pleiotropy
involved in calcium channel signaling with neurons. One of these genes, CACNA1C, has been found to influence cognition. It has been associated with autism
Apr 18th 2017



Malignant hyperthermia
Malignant hyperthermia (MH) or malignant hyperpyrexia is a rare life-threatening condition that is usually triggered by exposure to certain drugs used
Apr 28th 2017



Mir-137
VARS (Valyl-tRNA synthetase), L WBP1L (WW domain binding protein 1-like), CACNA1C (Calcium channel, voltage-dependent, L type, alpha 1C subunit), DPYD (Dihydropyrimidine
Apr 24th 2017



Physical exercise
"Workout" and "Exercise" redirect here. For other uses, see Workout (disambiguation) and Exercise (disambiguation). Physical exercise is any
Apr 25th 2017



List of OMIM disorder codes
601144; Brugada SCN5A Brugada syndrome 2; 611777; Brugada GPD1L Brugada syndrome 3; 611875; Brugada CACNA1C Brugada syndrome 4; 611876; CACNB2 Brugada syndrome 5; 612838; SCN1B Brugada
Sep 20th 2016



GAERS
The GAERS or Epilepsy-Rat">Genetic Epilepsy Absence Epilepsy Rat from Strasbourg is a recognized animal model of Epilepsy Absence Epilepsy, a typical childhood form of Epilepsy characterized
Apr 22nd 2016



Bipolar disorder
common single nucleotide polymorphisms, including variants within the genes CACNA1C, ODZ4, and NCAN. Advanced paternal age has been linked to a somewhat increased
Apr 23rd 2017



T-type calcium channel
T-type calcium channels are low-voltage activated calcium channels that open during membrane depolarization. These channels aid in mediating calcium influx
Apr 24th 2017



Cardiac action potential
α subunit gene Phase / role Na+ INa NaV1.5 SCN5A 0 Ca2+ ICa(L) CaV1.2 CACNA1C 0-2 K+ Ito1 KV4.2/4.3 KCND2/KCND3 1, notch K+ IKs KV7.1 KCNQ1 2,3 K+ IKr
Apr 27th 2017



Heritability of autism
The heritability of autism is the proportion of differences in expression of autism that can be explained by genetic variation; if the heritability of
Apr 1st 2017





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