Caveolin articles on Wikipedia
Caveolin
In molecular biology Caveolins are a family of integral membrane proteins that are the principal components of caveolae membranes and involved in receptor-independent
May 24th 2016



Caveolin 1
Caveolin-1 is a protein that in humans is encoded by the CAV1 gene. The scaffolding protein encoded by this gene is the main component of the caveolae
Jun 6th 2016



Caveolin 3
Caveolin-3 is a protein that in humans is encoded by the CAV3 gene. Alternative splicing has been identified for this locus, with inclusion or exclusion
May 28th 2016



Caveolin 2
coded Hope (Fraser Canyon Hospital) Heliport, see Hope, British Columbia. Caveolin-2 is a protein that in humans is encoded by the CAV2 gene. The protein
Jun 6th 2016



Caveolae
caveolins associate with lipid rafts and form oligomers (14-16 molecules). TheseThese oligomerized caveolins form the caveolae. The presence of caveolin leads
Mar 4th 2017



Nitric oxide synthase 2 (inducible)
different isoforms. Nitric oxide synthase 2A has been shown to interact with Caveolin 1 and Rac2. "Diseases that are genetically associated with NOS2 view/edit
May 27th 2016



CAV-1
similar may refer to: Infectious canine hepatitis, a virus disease of dogs Caveolin 1, a human gene Human genes that encode subunits of the slowly inactivating
Nov 7th 2016



Mir-802 microRNA precursor family
expression in the kidney is stimulated by a high potassium intake, along with caveolin-1 expression, one of the many miR-802 protein targets. Surface expression
Oct 27th 2016



Vesicular transport protein
molecules within a vesicle. Examples include: Archain ARFs Clathrin Caveolin Dynamin and related proteins, such as the EHD protein family Rab proteins
Apr 25th 2017



Dysferlin
Alzheimer's disease pathogenesis. Dysferlin has been shown to interact with Caveolin 3 in skeletal muscle., and this interaction is thought to retain dysferlin
Apr 26th 2017



TLR5
of Caveolin-1 in aging cells. Data from Caveolin-1 knockout mice demonstrated that TLR5 expression significantly decreases in the absence of Caveolin-1
Feb 19th 2017



MALL
glycolipid- and cholesterol-enriched membrane (GEM) rafts. It interacts with caveolin-1. "Human PubMed Reference:".  "Mouse PubMed Reference:".  Hildebrandt
Jun 2nd 2016



Reverse Warburg effect
dogma surrounding cancer cell metabolism, and explain the lethality of a caveolin 1 (Cav-1) deficient tumor microenvironment. More specifically, a loss of
Nov 30th 2016



Dystroglycan
2000). "CaveolinCaveolin-3 directly interacts with the C-terminal tail of beta -dystroglycan. Identification of a central WW-like domain within caveolin family
May 19th 2016



Antagomir
signalling. It has been shown that Caveolin-1-deficient mice show insulin resistance. MicroRNA-103/107 inhibition in Caveolin-1-deficient mice has no effect
Mar 1st 2017



PLD2
has been shown to interact with: ARF1, Aldolase A, Amphiphysin, BIN1, Caveolin 1, Glyceraldehyde 3-phosphate dehydrogenase, PLCG1, PRKCD, Src, and Wiskott-Aldrich
May 20th 2016



DNAJC14
Leclerc PC, AugerAuger-Messier M, Lanctot PM, et al. (2002). "A polyaromatic caveolin-binding-like motif in the cytoplasmic tail of the type 1 receptor for angiotensin
May 21st 2016



Inflammatory breast cancer
overexpressed, possibly related to overexpression (hypomethylation) of caveolin-1 and -2. Caveolin is paradoxically tumour promoting. NFB pathway activation overexpression
Nov 7th 2016



RAS p21 protein activator 1
P MP (September 2002). "Src-induced phosphorylation of caveolin-2 on tyrosine 19. PhosphoPhospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains
Jun 3rd 2016



TGF beta receptor 1
syndrome (LDS, LDAS). TGF beta receptor 1 has been shown to interact with: Caveolin 1, Endoglin, FKBP1A, FNTA, Heat shock protein 90kDa alpha (cytosolic),
Apr 17th 2017



Endothelial NOS
and direct interaction of eNOS with caveolin-1. The binding of calcium-activated calmodulin to eNOS displaces caveolin-1 and activates eNOS. Moreover, eNOS
Apr 27th 2017



Receptor-mediated endocytosis
their ligands can be brought into the cell through a few mechanisms (e.g. caveolin), clathrin-mediated endocytosis remains the best studied. Clathrin-mediated
Apr 28th 2017



MAL (gene)
PMID 9003426.  Millan J, Puertollano R, Fan L, Alonso MA (Apr 1997). "Caveolin and MAL, two protein components of internal detergent-insoluble membranes
Nov 20th 2016



ABCC9
Jiao J, Garg V, Yang B, et al. (2008). "Protein kinase C-epsilon induces caveolin-dependent internalization of vascular adenosine 5'-triphosphate-sensitive
Feb 6th 2017



SPRY4
Christofori G (Sep 2006). "A functional interaction between sprouty proteins and caveolin-1". The Journal of Biological Chemistry. 281 (39): 29201–12. doi:10.1074/jbc
May 20th 2016



SCP2
have impaired bile acid synthesis. SCP2 has been shown to interact with Caveolin 1 and peroxisomal receptor PEX5. "Human PubMed Reference:".  "Mouse
May 25th 2016



SPRY3
Christofori G (2006). "A functional interaction between sprouty proteins and caveolin-1.". J. Biol. Chem. 281 (39): 29201–2912. doi:10.1074/jbc.M603921200. PMID 16877379
Jun 3rd 2016



Endothelin receptor type B
frame overo. Endothelin receptor type B has been shown to interact with Caveolin 1. Agonists IRL-1620 Antagonists A-192,621 BQ-788 Bosentan (unselective
Dec 17th 2016



Congenital generalized lipodystrophy
mutation is caused by a mutation in the CAV1 gene. This gene codes for the Caveolin protein, which is a scaffolding membrane protein. This protein plays a
Apr 16th 2017



GJA1
protein, alpha 1 has been shown to interact with: Cx37, Cx40, Cx45, MAPK7, Caveolin 1, Tight junction protein 1 CSNK1D, and PTPmu (PTPRM). Mitochondria portal
Jun 13th 2016



Ramakrishnan Nagaraj
"Interaction of synthetic peptides corresponding to the scaffolding domain of Caveolin-3 with model membranes". Biopolymers. 84 (6): 615–24. doi:10.1002/bip.20595
Apr 12th 2017



Endostatin
Endostatin binding and clustering of integrins causes co-localization with caveolin-1 and activates non-receptor tyrosine kinases of the Src family involved
Jan 27th 2017



WNT3
2004.08.010. PMID 15588944.  Yamamoto H, Komekado H, Kikuchi A (2006). "Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation
Aug 8th 2016



AKAP1
Razani B, Lisanti MP (2001). "Two distinct caveolin-1 domains mediate the functional interaction of caveolin-1 with protein kinase A". Am. J. Physiol.
Dec 2nd 2016



5-HT1F receptor
Bhatnagar A, Sheffler DJ, Kroeze WK, Compton-Toth B, Roth BL (Aug 2004). "Caveolin-1 interacts with 5-HT2A serotonin receptors and profoundly modulates the
Apr 3rd 2017



STRN4
"Striatin, a calmodulin-dependent scaffolding protein, directly binds caveolin-1". FEBS Lett. 508 (1): 49–52. doi:10.1016/S0014-5793(01)03020-4. PMID 11707266
May 20th 2016



FZD5
1182/blood-2005-12-5046. PMID 16601243.  Yamamoto H, Komekado H, Kikuchi A (2006). "Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation
May 29th 2016



TGF beta receptor 2
Zhang XL, Bitzer M, von Gersdorff G, Bottinger EP, Lisanti MP (Mar 2001). "Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through
May 29th 2016



UBXN6
Weihl CC, Meyer H (August 2011). "Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations"
Apr 14th 2017



GJA3
"Connexin family members target to lipid raft domains and interact with caveolin-1". Biochemistry. 41 (18): 5754–64. doi:10.1021/bi0121656. PMID 11980479
Jun 13th 2016



ITPR3
PMID 18826956.  Sundivakkam PC, Kwiatek AM, Sharma TT, et al. (2009). "Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store
May 31st 2016



GRK5
Benovic JL (Mar 1999). "Regulation of G protein-coupled receptor kinases by caveolin". The Journal of Biological Chemistry. 274 (13): 8858–64. doi:10.1074/jbc
May 19th 2016



STRN
"Striatin, a calmodulin-dependent scaffolding protein, directly binds caveolin-1". FEBS Letters. 508 (1): 49–52. doi:10.1016/S0014-5793(01)03020-4. PMID 11707266
May 20th 2016



NEU3
"A close association of the ganglioside-specific sialidase Neu3 with caveolin in membrane microdomains". J. Biol. Chem. 277 (29): 26252–9. doi:10.1074/jbc
May 19th 2016



SPRY1
Christofori G (2006). "A functional interaction between sprouty proteins and caveolin-1.". J. Biol. Chem. 281 (39): 29201–2912. doi:10.1074/jbc.M603921200. PMID 16877379
Jun 3rd 2016



Ezetimibe
cells as well as in hepatocytes; blocks aminopeptidase N, and interrupts a Caveolin 1-Annexin A2 complex involved in trafficking cholesterol. Within 4–12
Mar 27th 2017



EMP2
S, et al. (2007). "The tetraspan protein EMP2 regulates expression of caveolin-1". J. Biol. Chem. 282 (36): 26542–51. doi:10.1074/jbc.M702117200. PMID 17609206
Jun 6th 2016



KLF11
Sp1/sterol-responsive element-binding protein-induced transcriptional activation of caveolin-1 in response to cholesterol signaling". The Journal of Biological Chemistry
Apr 17th 2017



MAL2 (gene)
PMC 528928. PMID 15489334.  Llorente A, de Marco MC, Alonso MA (2005). "Caveolin-1 and MAL are located on prostasomes secreted by the prostate cancer PC-3
Jun 2nd 2016



GP2 (gene)
the pancreatic acinar cell, co-immunoprecipitates with src kinases and caveolin". Pancreas. 21 (3): 219–25. doi:10.1097/00006676-200010000-00001. PMID 11039464
May 30th 2016





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